Both neoplastic and non-neoplastic bone and soft tissue pathology pose significant diagnostic challenges to the practicing pathologist, due to a lack of exposure to the broad range of entities and the diverse histologic spectrum of mesenchymal pathology. As the field is ever-evolving, new entities are described, and improved diagnostic techniques are introduced. This course, presented by expert educators, aims to introduce participants to newer entities, and refamiliarize learners to old challenges in the field. Participants will learn methods for distinguishing between histologically challenging tumors of bone and soft tissue, as well as recognizing features of non-neoplastic bone pathology.

Target Audience

Practicing academic and community pathologists, and pathologists-in-training

Learning Objectives

Upon completion of this educational activity, learners will be able to:
- Describe common non-neoplastic entities in bone and joint pathology and recognize their mimics
- Discuss the differential diagnosis for epithelioid and myxoid tumors of soft tissue and design a relevant panel of ancillary testing to aid in their distinction
- Develop a differential diagnosis for challenging bone tumors based on histologic and clinical-radiologic features
- Describe selected new entities in soft tissue pathology and apply immunohistochemical and molecular studies in their workup

Topics: 

• New Entities in Soft Tissue Neoplasia - Elizabeth G. Demicco, MD, PhD
• Challenging Bone and Soft Tissue Tumors - G. Pétur Nielsen, MD
• Epithelioid and/or Myxoid Tumors of Soft Tissue - Vickie Y. Jo, MD
• Non-neoplastic Bone and Joint Disease - Roberto A. Garcia, MD

Original release date: January 24, 2023
Access to this course expires on:  December 1, 2025